Friday, 8 October 2021

Yoghurt drink and prostate cancer



Source: The Times.

Prostate cancer patients may one day be given a yoghurt drink alongside drugs to boost their survival chances after scientists found that bugs in the gut could drive tumour growth and make treatment less effective.

Men with advanced prostate cancer are typically given therapy to lower their levels of androgens, male hormones, which their tumours need to grow. Some patients, however, develop resistance to that treatment.

A team led by the Institute for Cancer Research has found for the first time that bacteria in their guts could be responsible, with some species providing an alternative source of the hormones.

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The study, which will be published in the journal Science tomorrow, was funded by the Prostate Cancer Foundation, Movember, Prostate Cancer UK, Cancer Research UK and The John Black Charitable Foundation.

Dr Matthew Hobbs, director of research at Prostate Cancer UK, said: “We’re delighted to have helped fund this innovative, boundary-pushing research, which provides the first ever clues as to how ‘gut bugs’ might play a role in stopping prostate cancer becoming resistant to treatments.

“We urgently need to understand more about why treatments like androgen deprivation therapy eventually stop working, allowing men’s cancer to grow and progress. This research opens up a totally new avenue for us to explore — one which has potential to make a huge difference to men.”

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