Inflammation and Chronic Diseases: The Polar Lipid Link
Lordan R, Zabetakis I, Tsoupras A
Proceedings 2021, 70(1), 70; https://doi.org/10.3390/foods_2020-07598
Abstract
Cardiovascular diseases (CVD) are the leading cause of death globally.
The focus of scientists and practitioners for decades has been on
cholesterol levels and pharmacological ways to control them. Over the
past few years, a new school of thought has emerged: inflammation is the
underlying cause of chronic non-communicable diseases (NCDs) such as
CVD. Therefore, the key to reducing the incidence of chronic diseases is
to control the activities of various inflammatory mediators, such as
platelet-activating factor (PAF), via diet, exercise, and healthy
lifestyle choices. One proposal has been that the polar lipids (PL)
present in foods can play a key role via their antithrombotic and
anti-inflammatory bioactivities. In this paper, we present our latest
views on PAF and how it is related to CVD, and we discuss the role of
diet and PL against PAF-induced inflammation.
Keywords:
inflammation; chronic diseases; NCD; lipids; functional foods; nutraceuticals
the full paper is here.
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